International Validation of the Erasmus Guillain-Barre Syndrome Respiratory Insufficiency Score.

ABSTRACT:

Objective

This study aimed to validate the Erasmus Guillain-Barré Syndrome Respiratory Insufficiency Score in the International Guillain-Barré Syndrome Outcome Study cohort, and to improve its performance and region-specificity.

Methods

We examined data from the first 1,500 included patients, aged ≥6 years and not ventilated prior to study entry. Patients with a clinical variant or mild symptoms were also included. Outcome was mechanical ventilation within the first week from study entry. Model performance was assessed regarding the discriminative ability (area under the receiver operating characteristic curve) and the calibration (observed vs predicted probability of mechanical ventilation), in the full cohort and in Europe/North America and Asia separately. We recalibrated

SUBMITTER: Doets AY 

PROVIDER: S-EPMC9306880 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature