Alveolar crystal burden in stone workers with artificial stone silicosis.

ABSTRACT:

Background and objective

An epidemic of silicosis has emerged due to a failure to control risks associated with exposure to high-silica content respirable dust generated while working with artificial stone products. Methods for quantification of alveolar crystal burden are needed to advance our understanding of the pathobiology of silica-related lung injury as well as assisting in the diagnosis, clinical management and prognostication of affected workers. The objective of this study was to develop and validate novel methods to quantify alveolar crystal burden in bronchoalveolar lavage (BAL) fluid from patients with artificial stone silicosis.

Methods

New methods to quantify and analyse alveolar crystal in BAL from patients with artificial stone silicosis were developed. Crys

SUBMITTER: Apte SH 

PROVIDER: S-EPMC9307012 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature