An in silico approach to study the role of epitope order in the multi-epitope-based peptide (MEBP) vaccine design.

ABSTRACT: With different countries facing multiple waves, with some SARS-CoV-2 variants more deadly and virulent, the COVID-19 pandemic is becoming more dangerous by the day and the world is facing an even more dreadful extended pandemic with exponential positive cases and increasing death rates. There is an urgent need for more efficient and faster methods of vaccine development against SARS-CoV-2. Compared to experimental protocols, the opportunities to innovate are very high in immunoinformatics/in silico approaches, especially with the recent adoption of structural bioinformatics in peptide vaccine design. In recent times, multi-epitope-based peptide vaccine candidates (MEBPVCs) have shown extraordinarily high humoral and cellular responses to immunization. Most of the publications claim that re

SUBMITTER: Salaikumaran MR 

PROVIDER: S-EPMC9307121 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature