Partial masculinization of Aedes aegypti females by conditional expression of Nix.

ABSTRACT:

Background

Aedes aegypti, the main vector of dengue, yellow fever, and other arboviruses thrives in tropical and subtropical areas around the globe putting half of the world's population at risk. Despite aggressive efforts to control the transmission of those viruses, an unacceptable number of cases occur every year, emphasizing the need to develop new control strategies. Proposals for vector control focused on population suppression could offer a feasible alternative method to reduce disease transmission. The induction of extreme male-biased sex ratios has been hypothesized to be able to suppress or collapse a population, with previous experiments showing that stable expression of the male determining factor Nix in A. aegypti is sufficient to convert females into fertile males.

SUBMITTER: Kojin BB 

PROVIDER: S-EPMC9307153 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature