Human T-Lymphotropic virus type 1 and human immunodeficiency virus co-infection in rural Gabon.

ABSTRACT:

Introduction

Human T-cell lymphotrophic virus type-1 (HTLV-1) and human immunodeficiency virus (HIV-1) co-infection occur in many populations. People living with HIV-1 and infected with HTLV-1 seem more likely to progress rapidly towards AIDS. Both HTLV-1 and HIV-1 are endemic in Gabon (Central Africa). We investigated HTLV-1 and HIV-1 co-infection in the Haut-Ogooué province, and assessed factors that may favor the rapid evolution and progression to AIDS in co-infected patients.

Methods

Plasma samples from HTLV-1 patients were tested using ELISA, and positive samples were then tested by western blot assay (WB). We used the polymerase chain reaction to detect HTLV-1 Tax/Rex genes using DNA extracted from the buffy coat of ELISA-positives samples.

Results

We recruited

SUBMITTER: Mouinga-Ondeme A 

PROVIDER: S-EPMC9307203 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature