Increased risk of biliary infection after biliary stent placement in users of proton pump inhibitors.

ABSTRACT:

Objectives

Proton pump inhibitors (PPIs) are widely prescribed medications for gastric acid-induced diseases. Despite the effectiveness of PPIs, recent evidence suggested an increased risk of various bacterial infections in PPI users. The current study was conducted to evaluate the risk of biliary infection after endoscopic biliary stent placement in regular users of PPIs.

Methods

Consecutive patients with a native papilla who underwent endoscopic retrograde cholangiopancreatography and stent placement for biliary stricture between January 2010 and August 2019 were included in this retrospective study. The cumulative incidences of biliary infection were compared between regular and non-regular PPI users.

Results

During the study period, 270 regular PPI users and 146 n

SUBMITTER: Hakuta R 

PROVIDER: S-EPMC9307719 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature