Systematic review and meta-analysis of ivermectin for treatment of COVID-19: evidence beyond the hype.

ABSTRACT:

Background

The role of ivermectin in the treatment of COVID-19 is still under debate, yet the drug has been widely used in some parts of the world, as shown by impressive market data. The available body of evidence may have changed over the last months, as studies have been retracted and "standards of care" (SOC) used in control groups have changed with rapidly evolving knowledge on COVID-19. This review aims to summarize and critically appraise the evidence of randomized controlled trials (RCTs) of ivermectin, assessing clinical outcomes in COVID-19 patients.

Methods

RCTs evaluating the effects of ivermectin in adult patients with COVID-19 were searched through June 22, 2022, in four databases, L.OVE platform, clinical trial registries and pre-prints platforms. Primary endp

SUBMITTER: Marcolino MS 

PROVIDER: S-EPMC9308124 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature