CMIC: an efficient quality score compressor with random access functionality.

ABSTRACT:

Background

Over the past few decades, the emergence and maturation of new technologies have substantially reduced the cost of genome sequencing. As a result, the amount of genomic data that needs to be stored and transmitted has grown exponentially. For the standard sequencing data format, FASTQ, compression of the quality score is a key and difficult aspect of FASTQ file compression. Throughout the literature, we found that the majority of the current quality score compression methods do not support random access. Based on the above consideration, it is reasonable to investigate a lossless quality score compressor with a high compression rate, a fast compression and decompression speed, and support for random access.

Results

In this paper, we propose CMIC, an adaptive and r

SUBMITTER: Chen H 

PROVIDER: S-EPMC9308261 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature