Serial evaluation of thoracic radiographs and acute phase proteins in dogs with pneumonia.

ABSTRACT:

Background

Acute phase proteins (APP) may guide treatment of pneumonia in dogs but correlations with radiographic abnormalities are poorly characterized.

Objectives

Develop a thoracic radiographic severity scoring system (TRSS), assess correlation of radiographic changes with APP concentrations, and compare time to APP and radiograph normalization with duration of antimicrobials treatment.

Animals

Sixteen client-owned dogs, 12 with aspiration pneumonia, and 4 with community-acquired pneumonia.

Methods

Concentrations of C-reactive protein (CRP), serum amyloid A (SAA), and haptoglobin were measured on days 1, 3, 7, 14, 28, and 60 and orthogonal 2-view thoracic radiographs were obtained on days 1, 7, 14, 28, and 60. Treatment was clinician-guided and blinded to AP

SUBMITTER: Menard J 

PROVIDER: S-EPMC9308444 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature