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Multiple Simultaneous Infections With Nontuberculous Mycobacteria in the Setting of GATA2 Mutation and Myelodysplastic Syndrome.

ABSTRACT: GATA2 mutation can result in profoundly reduced monocytes, dendritic cells, natural killer cells, and B cells, and is associated with a predisposition for recurrent and disseminated nontuberculous mycobacterial (NTM) infections and myelodysplasias. Herein, we describe a unique case of 3 simultaneous disseminated NTM infections in a patient with GATA2 mutations.

SUBMITTER: Tabaja H

PROVIDER: S-EPMC9308453 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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Multiple Simultaneous Infections With Nontuberculous Mycobacteria in the Setting of GATA2 Mutation and Myelodysplastic Syndrome.

Tabaja Hussam H Jensen Kelsey L KL Rivera Christina G CG Misra Anisha A Pruthi Rajiv K RK Vergidis Paschalis P

Open forum infectious diseases 20220628 7

GATA2 mutation can result in profoundly reduced monocytes, dendritic cells, natural killer cells, and B cells, and is associated with a predisposition for recurrent and disseminated nontuberculous mycobacterial (NTM) infections and myelodysplasias. Herein, we describe a unique case of 3 simultaneous disseminated NTM infections in a patient with GATA2 mutations. ...[more]

PMID: 35891688

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