Moderate alcohol consumption and lipoprotein subfractions: a systematic review of intervention and observational studies.

ABSTRACT:

Context

Moderate alcohol consumption is associated with decreased risk of cardiovascular disease (CVD) and improvement in cardiovascular risk markers, including lipoproteins and lipoprotein subfractions.

Objective

To systematically review the relationship between moderate alcohol intake, lipoprotein subfractions, and related mechanisms.

Data sources

Following PRISMA, all human and ex vivo studies with an alcohol intake up to 60 g/d were included from 8 databases.

Data extraction

A total of 17 478 studies were screened, and data were extracted from 37 intervention and 77 observational studies.

Results

Alcohol intake was positively associated with all HDL subfractions. A few studies found lower levels of small LDLs, increased average LDL particle size, and

SUBMITTER: Wilkens TL 

PROVIDER: S-EPMC9308455 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature