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The translational revolution of itch.


ABSTRACT: The ability to sense the environment is essential to survival and is the primary purpose of the somatosensory nervous system. However, despite its highly conserved nature, the sensation of itch has been historically overlooked, and its importance in medicine underappreciated. Herein, we highlight how fundamental discoveries, coupled to rapid successes of new therapeutics, have placed itch biology at the forefront of a translational revolution in the field of somatosensation and beyond.

SUBMITTER: Kim BS 

PROVIDER: S-EPMC9308644 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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The translational revolution of itch.

Kim Brian S BS  

Neuron 20220420 14


The ability to sense the environment is essential to survival and is the primary purpose of the somatosensory nervous system. However, despite its highly conserved nature, the sensation of itch has been historically overlooked, and its importance in medicine underappreciated. Herein, we highlight how fundamental discoveries, coupled to rapid successes of new therapeutics, have placed itch biology at the forefront of a translational revolution in the field of somatosensation and beyond. ...[more]

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