Associations of Clinical and Social Risk Factors With Racial Differences in Premature Cardiovascular Disease.

ABSTRACT:

Background

Racial differences in cardiovascular disease (CVD) are likely related to differences in clinical and social factors. The relative contributions of these factors to Black-White differences in premature CVD have not been investigated.

Methods

In Black and White adults aged 18 to 30 years at baseline in the CARDIA study (Coronary Artery Risk Development in Young Adults), the associations of clinical, lifestyle, depression, socioeconomic, and neighborhood factors across young adulthood with racial differences in incident premature CVD were evaluated in sex-stratified, multivariable-adjusted Cox proportional hazards models using multiply imputed data assuming missing at random. Percent reduction in the β estimate (log-hazard ratio [HR]) for race quantified the contribu

SUBMITTER: Shah NS 

PROVIDER: S-EPMC9308688 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature