Non-dystrophic myotonia: 2-year clinical and patient reported outcomes.

ABSTRACT:

Introduction/aims

Consistency of differences between non-dystrophic myotonias over time measured by standardized clinical/patient-reported outcomes is lacking. Evaluation of longitudinal data could establish clinically relevant endpoints for future research.

Methods

Data from prospective observational study of 95 definite/clinically suspected non-dystrophic myotonia participants (six sites in the United States, United Kingdom, and Canada) between March 2006 and March 2009 were analyzed. Outcomes included: standardized symptom interview/exam, Short Form-36, Individualized Neuromuscular Quality of Life (INQoL), electrophysiological short/prolonged exercise tests, manual muscle testing, quantitative grip strength, modified get-up-and-go test. Patterns were assigned as described

SUBMITTER: Fullam TR 

PROVIDER: S-EPMC9308727 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature