Topical emollient application in term healthy newborns: A systematic review.

ABSTRACT:

Background

This systematic review of randomized trials assessed the effect of emollient application compared to no emollient application in term or near-term healthy newborns.

Methods

We searched MEDLINE via PubMed, Cochrane CENTRAL, Embase, and CINAHL (updated until November 2021), clinical trials databases, and reference lists of retrieved articles. Key outcomes were neonatal mortality, systemic infections, atopic dermatitis, skin condition, and adverse events. Two authors separately evaluated the risk of bias, extracted data, and synthesized effect estimates using relative risks (RR). The GRADE approach was used to assess the certainty of evidence.

Results

We screened 19 243 records and included 16 eligible trials involving 5643 participants. Five trials recruited

SUBMITTER: Priyadarshi M 

PROVIDER: S-EPMC9308984 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature