The Relationship Between Neighborhood Disadvantage and Kidney Disease Progression in the Chronic Kidney Disease in Children (CKiD) Cohort.

ABSTRACT:

Rationale & objective

To examine the relationship between neighborhood poverty and deprivation, chronic kidney disease (CKD) comorbidities, and disease progression in children with CKD.

Study design

Observational cohort study.

Setting & participants

Children with mild to moderate CKD enrolled in the CKiD (Chronic Kidney Disease in Children) study with available US Census data.

Exposure

Neighborhood poverty and neighborhood disadvantage.

Outcome

Binary outcomes of short stature, obesity, hypertension, and health care utilization for cross-sectional analysis; a CKD progression end point (incident kidney replacement therapy [KRT] or 50% loss in estimated glomerular filtration rate), and mode of first KRT for time-to-event analysis.

Analytical approach

SUBMITTER: Boynton SA 

PROVIDER: S-EPMC9309183 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature