Association Between Metformin Use and the Risk, Prognosis of Gynecologic Cancer.

ABSTRACT:

Background

For gynecological cancer patients, the beneficial effect of metformin use remains controversial due to inconsistent results of published articles. By conducting a meta-analysis, we aimed to evaluate the effect of metformin in reducing the risk and improving the survival of gynecological cancer among women with diabetes mellitus (DM).

Methods

Articles exploring association between metformin use and the risk, as well as prognosis of gynecologic cancer in DM, were searched in the databases: PubMed, Web of Science, SCOPUS, EMBASE, EBSCO, and PROQUEST. Articles were published before May 2022. All the studies were conducted using STATA 12.0 software.

Results

The meta-analysis showed no significant association between metformin use and risk of gynecologic cancer i

SUBMITTER: Yao K 

PROVIDER: S-EPMC9309370 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature