A transcriptomic dataset comparing two methods of hepatocyte differentiation from human induced pluripotent stem cells.

ABSTRACT: A variety of methods have been reported for the differentiation of hepatocyte-like cells (HLCs) from human induced pluripotent stem cells (iPSCs) using various growth factors or small molecules. However, direct comparison of the differentiation efficiency and the quality of the final HLCs between different methods has rarely been reported. To fill this data gap, we compared two hepatocyte differentiation methods, termed Method 1 and Method 2, and published the major findings in a research article entitled "Phenotypical, functional and transcriptomic comparison of two modified methods of hepatocyte differentiation from human induced pluripotent stem cells" (Li et al., 2022). The current data article describes the transcriptomic dataset comparing the two methods. HLCs were collected at early

SUBMITTER: Gao X 

PROVIDER: S-EPMC9309642 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature