High-Density, Actively Multiplexed μECoG Array on Reinforced Silicone Substrate.

ABSTRACT: Simultaneous interrogation of electrical signals from wide areas of the brain is vital for neuroscience research and can aid in understanding the mechanisms of brain function and treatments for neurological disorders. There emerges a demand for development of devices with highly conformal interfaces that can span large cortical regions, have sufficient spatial resolution, and chronic recording capability while keeping a small implantation footprint. In this work, we have designed 61 channel and 48 channel high-density, cortical, micro-electrocorticographic electrode arrays with 400 μm pitch on an ultra-soft but durable substrate. We have also developed a custom multiplexing integrated circuit (IC), methods for packaging the IC in a water-tight liquid crystal polymer casing, and a micro-bon

SUBMITTER: Rachinskiy I 

PROVIDER: S-EPMC9310058 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature