Effects of extreme temperature on the risk of preterm birth in China: A population-based multi-center cohort study.

ABSTRACT:

Background

Extreme temperatures are associated with the risk of preterm birth (PTB), but evidence on the effects of different clinical subtypes and across different regions is limited. We aimed to evaluate the effects of maternal exposure to extreme temperature on PTB and its clinical subtypes in China, and to identify effect modification of regional factors in dimensions of population, economy, medical resources and environmental factors.

Methods

This was a prospective population-based cohort of 210,798 singleton live births from 16 counties in eight provinces across China during 2014-2018. We used an extended Cox regression with time-varying variables to evaluate the effects of extreme heat and cold on PTB and its subtypes in the entire pregnancy, each trimester, the last

SUBMITTER: Ren M 

PROVIDER: S-EPMC9310344 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature