Identifying the source of spurious signals caused by B₀ inhomogeneities in single-voxel ¹ H MRS.

ABSTRACT:

Purpose

Single-voxel MRS (SV MRS) requires robust volume localization as well as optimized crusher and phase-cycling schemes to reduce artifacts arising from signal outside the volume of interest. However, due to local magnetic field gradients (B₀ inhomogeneities), signal that was dephased by the crusher gradients during acquisition might rephase, leading to artifacts in the spectrum. Here, we analyzed this mechanism, aiming to identify the source of signals arising from unwanted coherence pathways (spurious signals) in SV MRS from a B₀ map.

Methods

We investigated all possible coherence pathways associated with imperfect localization in a semi-localized by adiabatic selective refocusing (semi-LASER) sequence for potential rephasing of signals arising f

SUBMITTER: Shams Z 

PROVIDER: S-EPMC9311141 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature