Antidepressant medication use in Inflammatory Bowel Disease: a nationally representative population-based study.

ABSTRACT:

Background

Despite high rates of depression and anxiety, little is known about the use of antidepressants amongst individuals diagnosed with inflammatory bowel disease (IBD).

Aims

To evaluate temporal trends in the use of antidepressants; rates of antidepressant initiation and adherence of antidepressant use to international guidelines amongst individuals with IBD.

Methods

This is a study of 14,525 incident IBD cases from 2004 to 2016 compared with 58,027 controls matched 1:4 for age and sex from the Clinical Practice Research Datalink. After excluding tricyclic antidepressants, we performed a Cox regression analysis to determine the risk associated with antidepressant use and logistic regression analysis to determine risk associated with antidepressant undertreatment

SUBMITTER: Jayasooriya N 

PROVIDER: S-EPMC9311162 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature