Accumulation of endosymbiont genomes in an insect autosome followed by endosymbiont replacement.

ABSTRACT: Eukaryotic genomes can acquire bacterial DNA via lateral gene transfer (LGT).¹ A prominent source of LGT is Wolbachia,² a widespread endosymbiont of arthropods and nematodes that is transmitted maternally through female germline cells.^3,4 The DNA transfer from the Wolbachia endosymbiont wAna to Drosophila ananassae is extensive^5-7 and has been localized to chromosome 4, contributing to chromosome expansion in this lineage.⁶ As has happened frequently with claims of bacteria-to-eukaryote LGT, the contribution of wAna transfers to the expanded size of D. ananassae chromosome 4 has been specifically contested⁸ owing to an assembly where Wolbachia sequences were classified as contaminants and removed.⁹

SUBMITTER: Tvedte ES 

PROVIDER: S-EPMC9311232 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature