Chemical Characterization of Taif Rose (Rosa damascena) Methanolic Extract and Its Physiological Effect on Liver Functions, Blood Indices, Antioxidant Capacity, and Heart Vitality against Cadmium Chloride Toxicity.

ABSTRACT: Exposure to cadmium chloride (CdCl₂) causes an imbalance in the oxidant status of the body by triggering the release of reactive oxygen species (ROS). This study investigated the effect of Rosa damascena (R. damascena) extract on oxidative stress, hepatotoxicity, and the injured cardiac tissue of male rats exposed to CdCl₂. Forty male Wistar albino rats were divided into four groups: the vehicle control (1 mg/kg normal saline), the CdCl₂-treated group (5 mg/kg), the R. damascena extract group (100 mg Kg), and the combination of CdCl₂ and R. damascena extract group. Male rats exposed to CdCl₂ showed multiple significant histopathological changes in the liver and heart, including inflammatory cell infiltration

SUBMITTER: Hamza RZ 

PROVIDER: S-EPMC9311532 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature