Emerging Antibiotic Resistance Patterns Affect Visual Outcome Treating Acute Endophthalmitis.

ABSTRACT:

Background

Examining the effect of antibiotic resistance, use of intravitreal antibiotics and systemic corticosteroids on visual outcome of eyes with acute endophthalmitis.

Methods

We included 226 eyes with acute endophthalmitis, treated using a standardized protocol. Visual outcome up to 12 months was assessed related to biopsy results, antibiotics resistance and treatment regimens.

Results

Vitreous biopsies were more likely to be culture-positive (41.1%) than anterior chamber biopsies (21.6%, p < 0.0001). Antibiotic resistance for amikacin was found in 19 eyes (24.7%), vancomycin in 29 eyes (31.5%) and moxiflocacin in 14 eyes (16.1%). At presentation 91.53% of eyes had BCVA < 20/40, reducing by 1 month to 69.94% (p < 0.0001) and remaining stab

SUBMITTER: Wu XN 

PROVIDER: S-EPMC9311540 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature