Systematic Review of the "Pragmatism" of Pragmatic Critical Care Trials.

ABSTRACT: To assess the pragmatism of published critical care randomized controlled trials self-described as pragmatic using a validated tool.

Data sources

Medical Literature Analysis and Retrieval Online database and PubMed interface from inception to November 1, 2021.

Study selection

We performed a systematic search of randomized controlled trials evaluating interventions for critically ill adults that self-identified as pragmatic in title or abstract.

Data extraction

Reviewers independently performed study selection and data extraction in duplicate; discrepancies were resolved by consensus. Pragmatism was assessed independently in duplicate by trained reviewers using the Pragmatic-Explanatory Continuum Indicator Summary 2 (PRECIS-2), a validated tool designed to represent how

SUBMITTER: Palakshappa JA 

PROVIDER: S-EPMC9312432 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature