Longitudinal Study of Cognitive Functioning in Adults with Juvenile Idiopathic Arthritis.

ABSTRACT:

Objective

To prospectively evaluate possible decline of cognitive functions in adult patients with juvenile idiopathic arthritis (JIA) and identify associated factors.

Patients and methods

We performed a 24-month prospective observational study of adults (≥16 years) with JIA. The primary outcome measure was decline in cognitive function defined as a worsening of ≥2 points on the scales of the subsets administered to evaluate the different cognitive areas using the Wechsler Adult Intelligence Scale (WAIS) after 24 months: attention/concentration (digit span); verbal function (vocabulary); visual-spatial organization (block design); working memory (letter-number sequencing); and problem solving (similarities). Other variables included average inflammatory activity using C-reac

SUBMITTER: Mena-Vazquez N 

PROVIDER: S-EPMC9312867 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature