Nomogram for Predicting Depression Improvement after Deep Brain Stimulation for Parkinson's Disease.

ABSTRACT:

Background

Parkinson's disease is a common neurodegenerative disease, with depression being a common non-motor symptom. Bilateral subthalamic nucleus deep brain stimulation is an effective method for the treatment of Parkinson's disease. Thus, this study aimed to establish a nomogram of the possibility of achieving a better depression improvement rate after subthalamic nucleus deep brain stimulation in patients with Parkinson's disease.

Methods

We retrospectively analyzed 103 patients with Parkinson's disease who underwent subthalamic nucleus deep brain stimulation and were followed up for the improvement of their Hamilton Depression scale scores 1 year postoperatively. Univariate and multivariate logistic regression analyses were used to select factors affecting the improve

SUBMITTER: Chang B 

PROVIDER: S-EPMC9313072 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature