Biofilm Detection by a Fiber-Tip Ball Resonator Optical Fiber Sensor.

ABSTRACT: Bacterial biofilms are one of the most important challenges that modern medicine faces due to the difficulties of diagnosis, antibiotic resistance, and protective mechanisms against aggressive environments. For these reasons, methods that ensure the inexpensive and rapid or real-time detection of biofilm formation on medical devices are needed. This study examines the possibilities of using optical- and fiber-based biosensors to detect and analyze early bacterial biofilms. In this study, the biofilm-forming model organism Pseudomonas aeruginosa was inoculated on the surface of the optical sensor and allowed to attach for 2 h. The biosensors were made by a fiber-tip ball resonator, fabricated through a CO₂ laser splicer on a single-mode fiber, forming a weak reflective spe

SUBMITTER: Rakhimbekova A 

PROVIDER: S-EPMC9313161 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature