Dataset Information

Enhancer-LSTMAtt: A Bi-LSTM and Attention-Based Deep Learning Method for Enhancer Recognition.

ABSTRACT: Enhancers are short DNA segments that play a key role in biological processes, such as accelerating transcription of target genes. Since the enhancer resides anywhere in a genome sequence, it is difficult to precisely identify enhancers. We presented a bi-directional long-short term memory (Bi-LSTM) and attention-based deep learning method (Enhancer-LSTMAtt) for enhancer recognition. Enhancer-LSTMAtt is an end-to-end deep learning model that consists mainly of deep residual neural network, Bi-LSTM, and feed-forward attention. We extensively compared the Enhancer-LSTMAtt with 19 state-of-the-art methods by 5-fold cross validation, 10-fold cross validation and independent test. Enhancer-LSTMAtt achieved competitive performances, especially in the independent test. We realized Enhancer-LSTMAtt into a user-friendly web application. Enhancer-LSTMAtt is applicable not only to recognizing enhancers, but also to distinguishing strong enhancer from weak enhancers. Enhancer-LSTMAtt is believed to become a promising tool for identifying enhancers.

SUBMITTER: Huang G

PROVIDER: S-EPMC9313278 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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Publications

Enhancer-LSTMAtt: A Bi-LSTM and Attention-Based Deep Learning Method for Enhancer Recognition.

Huang Guohua G Luo Wei W Zhang Guiyang G Zheng Peijie P Yao Yuhua Y Lyu Jianyi J Liu Yuewu Y Wei Dong-Qing DQ

Biomolecules 20220717 7

Enhancers are short DNA segments that play a key role in biological processes, such as accelerating transcription of target genes. Since the enhancer resides anywhere in a genome sequence, it is difficult to precisely identify enhancers. We presented a bi-directional long-short term memory (Bi-LSTM) and attention-based deep learning method (Enhancer-LSTMAtt) for enhancer recognition. Enhancer-LSTMAtt is an end-to-end deep learning model that consists mainly of deep residual neural network, Bi-LS ...[more]

PMID: 35883552

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Project description:The prediction of energy consumption in households is essential due to the reliance on electrical appliances for daily activities. Accurate assessment of energy demand is crucial for effective energy generation, preventing overloads and optimizing energy storage. Traditional techniques have limitations in accuracy and error rates, necessitating advancements in prediction techniques. To enhance prediction accuracy, a proposed smart city system utilizes the Household Energy Consumption dataset, employing deep learning algorithms. In the beginning, data pre-processing addresses missing values and performs feature scaling for normalizing independent variables. Followed by that, Modified Deep CNN-Bi-LSTM (Convolutional Neural Network and Bi-directional Long Short Term Memory) with attention mechanism is utilized for regression which extracts temporal and spatial complex features. Deep CNN extracts features impacting energy consumption whereas Bi-LSTM with attention layer finds suitability for regression as it is capable of modelling irregular trends in the time-series components, where the attention mechanism is implemented to enhance the decoder's ability to selectively focus on the most relevant segments of the input sequence. This is achieved through a weighted integration of all encoded input trajectories, allowing the model to dynamically emphasize the vectors that carry the highest significance for accurate predictions. Based on regression outcomes from analysis taken in hourly, daily and monthly time intervals, enhanced prediction accuracy is estimated through evaluation metrics such as MSE (Mean Square Error), MAPE (Mean Absolute Percentage Error) and RMSE (Root Mean Square Error) which determines the efficacy of the system, where Specifically, the proposed model achieves MSE of 0.123, MAE of 0.22, and MAPE of 324.12. Furthermore, this model demonstrates a training time of 692.12 s and a prediction time of just 1.87 s. Therefore, present research highlights the critical need for accurate energy consumption prediction in households, driven by the increasing reliance on electrical appliances in daily life.

Dataset Information

Enhancer-LSTMAtt: A Bi-LSTM and Attention-Based Deep Learning Method for Enhancer Recognition.

Publications

Enhancer-LSTMAtt: A Bi-LSTM and Attention-Based Deep Learning Method for Enhancer Recognition.

Similar Datasets

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