The prognostic value of extramural venous invasion in preoperative MRI of rectal cancer patients.

ABSTRACT:

Aim

This study aimed to examine the prognostic value of extramural venous invasion observed in preoperative MRI on survival and recurrences.

Method

In total, 778 rectal cancer patients were evaluated in multidisciplinary meetings in Helsinki University Hospital during the years 2016-2018. 635 patients met the inclusion criteria of stage I-III disease and were intended for curative treatment at the time of diagnosis. 128 had extramural venous invasion in preoperative MRI.

Results

The median follow-up time was 2.5 years. In a univariate analysis extramural venous invasion was associated with poorer disease-specific survival (hazard ratio [HR] 2.174, 95% CI 1.118-4.224, P = 0.022), whereas circumferential margin ≤1 mm, tumour stage ≥T3c or nodal positivity were not. Dise

SUBMITTER: Lehtonen TM 

PROVIDER: S-EPMC9314139 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature