Age-Related Sex Disparities in Esophageal Cancer Survival: A Population-Based Study in the United States.

ABSTRACT:

Background

The association between sex and the survival of patients with esophageal cancer (EC) remains controversial. We sought to systematically investigate sex-based disparities in EC survival using the Surveillance, Epidemiology, and End Results (SEER) registry data from the United States.

Methods

Patients with EC diagnosed from 2004 to 2015 registered in the SEER database were selected. The association between sex and cancer-specific survival (CSS) was evaluated using survival analysis. The Inverse Probability Weighting (IPW) approach was applied to reduce the observed bias between males and females. Subgroup analyses were used to investigate the robustness of the sex-based disparity and to explore potential interaction effects with other variables.

Results

Overa

SUBMITTER: Xiang ZF 

PROVIDER: S-EPMC9314568 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature