Non-surgical peri-implantitis treatment with or without systemic antibiotics: a randomized controlled clinical trial.

ABSTRACT:

Objectives

To assess the adjunctive effect of systemic amoxicillin (AMX) and metronidazole (MTZ) in patients receiving non-surgical treatment (NST) for peri-implantitis (PI).

Materials and methods

Thirty-seven patients were randomized into an experimental group treated with NST plus AMX + MTZ (N = 18) and a control group treated with NST alone (N = 19). Clinical parameters were evaluated at 12 weeks post-treatment. The primary outcome was the change in peri-implant pocket depth (PIPD) from baseline to 12 weeks, while secondary outcomes included bleeding on probing (BoP), suppuration on probing (SoP), and plaque. Data analysis was performed at patient level (one target site per patient).

Results

All 37 patients completed the study. Both groups showed a significant PIPD

SUBMITTER: Polymeri A 

PROVIDER: S-EPMC9314590 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature