Joint status of patients with nonsevere hemophilia A.

ABSTRACT:

Background

Joint bleeding in hemophilia may eventually lead to joint damage. In nonsevere hemophilia, joint bleeds occur infrequently. Currently, knowledge on the joint status of patients with nonsevere hemophilia using objective imaging is limited.

Objective

To investigate the joint status in patients with nonsevere hemophilia A.

Methods

This cross-sectional study included patients with nonsevere hemophilia A aged 24-55 years. Joint status was assessed by magnetic resonance imaging (MRI) of the elbows, knees, and ankles and International Prophylaxis Study Group (IPSG) scores were calculated. Lifetime joint bleeding history was collected from medical files. The contribution of factors to joint outcome was explored using multivariable linear regression analysis.

Res

SUBMITTER: Zwagemaker AF 

PROVIDER: S-EPMC9314729 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature