Trends in cocirculation of oncogenic HPV genotypes in single and multiple infections among the unvaccinated community.

ABSTRACT: Cocirculation of multiple human papillomavirus (HPV) infections with low, probably high, and high-risk genotypes are to be associated with various grades of infections and cancer progression. The oncogenic high-risk HPVs are distributed and cocirculated throughout the world. This study was investigated to identify HPV genotypes related to genital disorders in unvaccinated women. The subjects were referred from clinics to a molecular lab for HPV testing in Iran as a low-coverage vaccinated country. HPVs DNAs of cervical scrapping and genital tissue specimens of 1,133 un-vaccinated women were genotyped using an in vitro diagnostic line probe (reverse hybridization) assay. In addition, phylogenetic trees were constructed on 100 MY09/MY11 polymerase chain reaction (PCR) amplicons of common gen

SUBMITTER: Vazifehdoost M 

PROVIDER: S-EPMC9314791 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature