Validation of four cutaneous squamous cell carcinoma staging systems using nationwide data.

ABSTRACT:

Background

Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer worldwide with relatively low metastatic potential (2-5%). Developments in therapeutic options have highlighted the need to better identify high-risk patients who could benefit from closer surveillance, adjuvant therapies and baseline/follow-up imaging, while at the same time safely omitting low-risk patients from further follow-up. Controversy remains regarding the predictive performance of current cSCC staging systems and which methodology to adopt.

Objectives

To validate the performance of four cSCC staging systems [American Joint Committee on Cancer 8th edition (AJCC8), Brigham and Women's Hospital (BWH), Tübingen and Salamanca T3 refinement] in predicting metastasis using a nationwide c

SUBMITTER: Venables ZC 

PROVIDER: S-EPMC9315012 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature