Parallel transmit pulse design for saturation homogeneity (PUSH) for magnetization transfer imaging at 7T.

ABSTRACT:

Purpose

This work proposes a novel RF pulse design for parallel transmit (pTx) systems to obtain uniform saturation of semisolid magnetization for magnetization transfer (MT) contrast in the presence of transmit field B1+ inhomogeneities. The semisolid magnetization is usually modeled as being purely longitudinal, with the applied B1+ field saturating but not rotating its magnetization; thus, standard pTx pulse design methods do not apply.

Theory and methods

Pulse design for saturation homogeneity (PUSH) optimizes pTx RF pulses by considering uniformity of root-mean squared B1+ , B1rms , which relates to the rate of semisolid saturation. Here we considered designs consisting of a small number of spatially non-selective sub-pulses optimized over either a single 2D plane or 3D

SUBMITTER: Leitao D 

PROVIDER: S-EPMC9315051 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature