Exact breakpoints of the In(1)w m4 rearrangement.
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ABSTRACT:
SUBMITTER: Solodovnikov A
PROVIDER: S-EPMC9315410 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Publications
Exact breakpoints of the <i>In(1)w <sup>m4</sup></i> rearrangement.
Solodovnikov Alexander A Lavrov Sergey S
microPublication biology 20220725
<i>In(1)w <sup>m4</sup></i> has been known for decades as a classic example of a position effect variegation-causing rearrangement and has been mentioned in hundreds of publications. Nevertheless, its euchromatic breakpoint has not been localized with base-pair resolution. We performed nanopore sequencing of DNA from <i>In(1)w <sup>m4</sup></i> homozygous flies and determined the exact position of euchromatic (chrX:2767875) and heterochromatic breakpoints of the rearrangement. The heterochromati ...[more]
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