Intra-Species Genomic Variation in the Pine Pathogen Fusarium circinatum.

ABSTRACT: Fusarium circinatum is an important global pathogen of pine trees. Genome plasticity has been observed in different isolates of the fungus, but no genome comparisons are available. To address this gap, we sequenced and assembled to chromosome level five isolates of F. circinatum. These genomes were analysed together with previously published genomes of F. circinatum isolates, FSP34 and KS17. Multi-sample variant calling identified a total of 461,683 micro variants (SNPs and small indels) and a total of 1828 macro structural variants of which 1717 were copy number variants and 111 were inversions. The variant density was higher on the sub-telomeric regions of chromosomes. Variant annotation revealed that genes involved in transcription, transport, metabolism and transme

SUBMITTER: Maphosa MN 

PROVIDER: S-EPMC9316270 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature