Effect of multicomponent exercise in cognitive impairment: a systematic review and meta-analysis.

ABSTRACT:

Background

Multicomponent physical exercise is the most recommended type of physical intervention in older adults. Experimental data suggest the relevance of the muscle-brain axis and the relationship between muscle contraction and release of brain-derived neurotrophic factor, however, the impact of this relationship on cognition remains unclear, especially in people with diagnosis of cognitive impairment. This study assesses the effect of multicomponent physical exercise on global cognition in people with mild cognitive impairment or dementia.

Methods

Randomized controlled trials published until January 2021 were searched across three electronic databases (PubMed, Scopus, and Cochrane Database). Data about exercises included in the multicomponent intervention (endurance, st

SUBMITTER: Venegas-Sanabria LC 

PROVIDER: S-EPMC9316334 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature