Unraveling the Diversity of Co-Colonization by CPE.

ABSTRACT: Antibiotic-resistant bacteria, and more specifically, carbapenem-producing Enterobacterales (CPE) strains, are increasing worldwide. Despite their growing prevalence, in most high-income countries, the detection of CPE is still considered a low-frequency event. Sporadically, patients co-colonized with distinct CPE strains and/or different carbapenemase enzymes are detected. In this paper, we present three cases that illustrate the underlying mechanisms of co-colonization, focusing on horizontal gene transfer (HGT) and patient-to-patient transmission. We also demonstrate the diversity of CPE species and discuss the potential consequences of co-colonization.

SUBMITTER: Levi G 

PROVIDER: S-EPMC9316973 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature