Lights and Shadows on the Therapeutic Use of Antimicrobial Peptides.

ABSTRACT: The emergence of antimicrobial-resistant infections is still a major concern for public health worldwide. The number of pathogenic microorganisms capable of resisting common therapeutic treatments are constantly increasing, highlighting the need of innovative and more effective drugs. This phenomenon is strictly connected to the rapid metabolism of microorganisms: due to the huge number of mutations that can occur in a relatively short time, a colony can "adapt" to the pharmacological treatment with the evolution of new resistant species. However, the shortage of available antimicrobial drugs in clinical use is also caused by the high costs involved in developing and marketing new drugs without an adequate guarantee of an economic return; therefore, the pharmaceutical companies have reduce

SUBMITTER: Bellotti D 

PROVIDER: S-EPMC9317528 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature