Association between Age of Onset of Hypertension and Incident Atrial Fibrillation.

ABSTRACT: We investigated whether age at hypertension (HTN) onset was associated with the risk of atrial fibrillation (AF) in the general population. This prospective longitudinal community-based cohort study included 9892 participants without AF at baseline, who underwent biennial electrocardiography for a median duration of 11.5 years. The participants were divided into five groups, consisting of a normotensive group (Group-N) and four HTN groups based on HTN onset age: <45 years (Group-H1); 45-54 years (Group-H2); 55-64 years (Group-H3); and ≥65 years (Group-H4). A multivariate Cox proportional hazards model showed that the presence of HTN at baseline was associated with higher AF risk (hazard ratio [HR], 1.93; 95% confidence interval [CI] 1.32-2.80). The participants in Group-H1 had the highe

SUBMITTER: Lee Y 

PROVIDER: S-EPMC9317856 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature