Milk Oral Lyophilizates with Loratadine: Screening for New Excipients for Pediatric Use.

ABSTRACT: The development of suitable formulations for the pediatric population remains a challenging field with great advances reported every year in terms of excipients and technology. When developing pediatric formulations, the acceptability of medicines represents a key element to consider. For this reason, milk can be a widely accepted excipient with taste-masking properties and supplementary advantages for drug solubility. In recent years, the orodispersible dosage forms have come onto the market as child-friendly formulations. The current study aimed to develop freeze-dried orodispersible dosage forms containing bovine milk or infant formulae as the main component. In the first stage, an exploratory study evaluated the mechanical properties of placebo milk formulations and the suitability of

SUBMITTER: Iurian S 

PROVIDER: S-EPMC9318030 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature