Pharmacological Potential of Lathyrane-Type Diterpenoids from Phytochemical Sources.

ABSTRACT: Lathyrane diterpenoids are one of the primary types of secondary metabolites present in the genus Euphorbia and one of the largest groups of diterpenes. They are characterized by having a highly oxygenated tricyclic system of 5, 11 and 3 members. These natural products and some synthetic derivatives have shown numerous interesting biological activities with clinical potential against various diseases, such as cytotoxic activity against cancer cell lines, multi-drug resistance reversal, antiviral properties, anti-inflammatory activity and their capability to induce proliferation or differentiation into neurons of neural progenitor cells. The structure of the lathyrane skeleton could be considered privileged because its framework is able to direct functional groups in a well-defined s

SUBMITTER: Vela F 

PROVIDER: S-EPMC9318715 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature