Random Mutagenesis as a Promising Tool for Microalgal Strain Improvement towards Industrial Production.

ABSTRACT: Microalgae have become a promising novel and sustainable feedstock for meeting the rising demand for food and feed. However, microalgae-based products are currently hindered by high production costs. One major reason for this is that commonly cultivated wildtype strains do not possess the robustness and productivity required for successful industrial production. Several strain improvement technologies have been developed towards creating more stress tolerant and productive strains. While classical methods of forward genetics have been extensively used to determine gene function of randomly generated mutants, reverse genetics has been explored to generate specific mutations and target phenotypes. Site-directed mutagenesis can be accomplished by employing different gene editing tools, which

SUBMITTER: Trovao M 

PROVIDER: S-EPMC9318807 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature