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ABSTRACT: Background
A growing number of cohort studies revealed an inverse association between cheese intake and cardiovascular diseases, yet the causal relationship is unclear.Objective
To assess the causal relationship between cheese intake, and cardiovascular diseases and cardiovascular biomarkers.Methods
A two-sample Mendelian randomization (MR) analysis based on publicly available genome-wide association studies was employed to infer the causal relationship. The effect estimates were calculated using the random-effects inverse-variance-weighted method.Results
Cheese intake per standard deviation increase causally reduced the risks of type 2 diabetes (odds ratio (OR) = 0.46; 95% confidence interval (CI), 0.34-0.63; p = 1.02 × 10-6), heart failur
SUBMITTER: Hu MJ
PROVIDER: S-EPMC9318947 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature