Alteration in Gut Microbiota Associated with Zinc Deficiency in School-Age Children.

ABSTRACT: Zinc deficiency could lead to a dynamic variation in gut microbial composition and function in animals. However, how zinc deficiency affects the gut microbiome in school-age children remains unclear. The purpose of this study was to profile the dynamic shifts in the gut microbiome of school-age children with zinc deficiency, and to determine whether such shifts are associated with dietary intake. A dietary survey, anthropometric measurements, and serum tests were performed on 177 school-age children, and 67 children were selected to explore the gut microbial community using amplicon sequencing. School-age children suffered from poor dietary diversity and insufficient food and nutrient intake, and 32% of them were zinc deficient. The inflammatory cytokines significantly increased in the zin

SUBMITTER: Chen X 

PROVIDER: S-EPMC9319427 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature