Ontology highlight
ABSTRACT:
SUBMITTER: Gupta A
PROVIDER: S-EPMC9320009 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Gupta Anubhuti A Singh Kunal K Fatima Sameen S Ambreen Saira S Zimmermann Silke S Younis Ruaa R Krishnan Shruthi S Rana Rajiv R Gadi Ihsan I Schwab Constantin C Biemann Ronald R Shahzad Khurrum K Rani Vibha V Ali Shakir S Mertens Peter Rene PR Kohli Shrey S Isermann Berend B
Nutrients 20220720 14
Diabetes mellitus is a metabolic disease largely due to lifestyle and nutritional imbalance, resulting in insulin resistance, hyperglycemia and vascular complications. Diabetic kidney disease (DKD) is a major cause of end-stage renal failure contributing to morbidity and mortality worldwide. Therapeutic options to prevent or reverse DKD progression are limited. Endothelial and glomerular filtration barrier (GFB) dysfunction and sterile inflammation are associated with DKD. Neutrophil extracellul ...[more]