Genomic Comparisons of Alphacoronaviruses and Betacoronaviruses from Korean Bats.

ABSTRACT: Coronaviruses are well known as a diverse family of viruses that affect a wide range of hosts. Since the outbreak of severe acute respiratory syndrome, a variety of bat-associated coronaviruses have been identified in many countries. However, they do not represent all the specific geographic locations of their hosts. In this study, full-length genomes representing newly identified bat coronaviruses in South Korea were obtained using an RNA sequencing approach. The analysis, based on genome structure, conserved replicase domains, spike gene, and nucleocapsid genes revealed that bat Alphacoronaviruses are from three different viral species. Among them, the newly identified B20-97 strain may represent a new putative species, closely related to PEDV. In addition, the newly-identified MERS-rela

SUBMITTER: Lo VT 

PROVIDER: S-EPMC9320528 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature